Overview
Vascular Endothelial Growth Factor (VEGF165) is a representative growth factor that regulates angiogenesis, promoting the proliferation and migration of endothelial cells. It binds to VEGF receptors to induce signal transduction related to cell survival, vascular permeability, and tissue regeneration. This recombinant VEGF is produced through an E. coli expression system, offering high purity and stable activity for application in a wide range of research and formulation contexts.
Applications
- Angiogenesis and blood vessel formation research
- Endothelial cell proliferation and migration studies
- VEGF signaling pathway research
- Tissue regeneration and wound healing studies
- Skin regeneration and repair formulations
- Circulation-improving and skin revitalizing products
- Anti-aging and skin improvement products
- Scalp and hair growth-related formulations
Properties
| Item | Description |
|---|---|
| Product name | VEGF (Vascular endothelial growth factor 165, human) |
| Manufacturing Source | Recombinant, E. coli |
| Purity | ≥ 98 %, as determined by Coomassie stained SDS-PAGE. |
| Endotoxin | ≤ 0.4 EU/μg of protein |
| Protein Content | Quantified using validated methods |
| Biological activity | ED50 ≤ 40 ng/mL (HUVEC cell proliferation assay) |
| Predicted N terminal | Met1 |
| Molecular Weight | 19297.1 Da (166 amino acids). |
| Formulation | Sterile filtered through a 0.2 micron filtered 1X DPBS, pH 7.4. |
| Storage and Stability | Store at 2–8 °C for short-term use (1–2 weeks) and at -20 °C or below for long-term storage (> 2 weeks). Avoid repeated freeze–thaw cycles. |