Product Overview

Overview

Platelet-Derived Growth Factor AA (PDGF-AA) is a signaling protein and growth factor that regulates cell growth and differentiation, acting across diverse cell types. It particularly promotes the proliferation of fibroblasts and mesenchymal cells, and is involved in angiogenesis and tissue regeneration processes. This recombinant PDGF-AA is produced through an E. coli expression system, offering high purity and stable activity for application in a wide range of research and formulation contexts.

Application Area

Applications

Research Applications
  • Cell proliferation assay (NIH 3T3, etc.)
  • Fibroblast and mesenchymal cell studies
  • Angiogenesis and tissue regeneration research
  • Growth factor signal transduction studies
Cosmetic Applications
  • Skin regeneration and repair formulations
  • Wrinkle improvement and elasticity enhancement products
  • Damaged skin improvement and repair products
Properties

Properties

ItemDescription
Product namePDGF AA (Platelet-derived growth factor AA, human)
Manufacturing SourceRecombinant, E. coli
Purity≥ 98 %, as determined by Coomassie stained SDS-PAGE
Endotoxin< 0.4 EU/μg of protein
Protein ContentQuantified using validated methods
Biological activityED50 ≤ 50 ng/mL (NIH 3T3 cell proliferation assay)
Predicted N terminalMet1
Molecular Weight14436.79 Da (126 amino acids).
FormulationSterile filtered through a 0.2 micron filtered 50 mM sodium phosphate, 100 mM NaCl, pH 7.0.
Storage and StabilityStore at 2–8 °C for short-term use (1–2 weeks) and at -20 °C or below for long-term storage (> 2 weeks). Avoid repeated freeze–thaw cycles.
PDGF AA Activity Data