PROCELL 
PC-BoLC is a transdermal delivery-type recombinant protein in which the MTD skin-penetrating domain is fused to the Light Chain — the active domain of botulinum toxin. It maximizes delivery efficiency into nerve cells to selectively cleave SNAP-25, blocking acetylcholine release to relax excessive muscle contractions for superior wrinkle improvement. Designed using only the active domain rather than the full toxin, it minimizes the possibility of antibody formation (resistance) for stable efficacy even with repeated use.
| Item | Description |
|---|---|
| Product Name | PC-BoLC (MTD-BoLC) |
| INCI Name | Methionyl r-Clostridium Botulinum Polypeptide-1 Hexapeptide-40 |
| Category | Recombinant protein (Growth factor) |
| Manufacturing Source | E.coli |
| Appearance | Clear and colourless solution |
| Purity (%) | ≥ 90.0 % |
| Molecular Weight | 53 kDa |
| Recommended Dose | ≤ 2 ppm |
| Content | 1 mg to gram-scale |
| Applications | Skin care & Body care |
| Recommended use | Anti-wrinkle, Skin lifting, Wound healing |
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Anti-Wrinkle Cosmetic Ingredient: Applied in expression line reduction and skin elasticity care products
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Anti-Aging Cosmetic Ingredient: Used in skin aging management and conditioning products
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Skin Elasticity Care Ingredient: Applied in tension-relieving elasticity management products
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High-Performance Skincare Ingredient: Applied in premium ampoules, serums, and similar products
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Protein Cosmetic Ingredient: Applicable to various formulations
PC-BoLC helps reduce expression wrinkles to achieve a smoother and more refined skin appearance.
PC-BoLC modulates neurotransmission to relax muscle contractions and contribute to reduced wrinkle formation.
PC-BoLC helps improve skin tension to maintain firmer and more lifted skin.
PC-BoLC contributes to reducing signs of aging through skin structural improvement.
PC-BoLC enhances transdermal penetration and neuronal delivery efficiency to maximize the action of active components.
Anti-Wrinkle
Muscle Contraction Inhibition
Firming & Elasticity
Anti-Aging
Enhanced Delivery
Patented Platform for Superior Efficacy
ProCell's patented delivery technology optimizes the delivery structure and action environment of active ingredients for stable and consistent efficacy expression.
Delivers active ingredients into cells, inducing direct intracellular action and enabling fundamental efficacy at the cellular level.
Effectively penetrates the skin barrier, allowing active ingredients to reach target sites while minimizing loss during delivery to maximize action efficiency.
The combination of delivery technology and active ingredient properties enables efficient action compared to conventional ingredients, achieving high efficacy even at lower concentrations.
Frequently Asked Questions
What role do botulinum-derived ingredients play?
They are cosmetic ingredients that help reduce wrinkles formed by facial expression movements, based on mechanisms related to neurotransmission processes.
Is PC-BoLC the same as conventional botulinum toxin?
It is not the same complete toxin form; rather, it is a cosmetic protein designed as a light chain protein-based ingredient utilizing functional characteristics.
Is it safe to use botulinum-derived ingredients in cosmetics?
When applied as a cosmetic ingredient, it is designed as a specific functional protein form rather than the complete toxin, and is developed in accordance with cosmetic application standards.
What are its characteristics as an anti-wrinkle ingredient?
It is a mechanism-based ingredient that reduces wrinkles formed by repetitive facial movements, enabling a different anti-aging care approach from conventional elasticity-focused ingredients.
How does it differ from peptide-based anti-wrinkle ingredients?
While targeting similar functions, it differs in mechanism of action and structural characteristics as a protein-based ingredient.
What products can it be applied to?
It is applied in wrinkle improvement, anti-aging, and skin elasticity care products, and used in various skincare formulations including serums, ampoules, and creams.
How is PC-BoLC different from conventional cosmetic ingredients?
PC-BoLC is a protein ingredient designed with transdermal delivery technology for more effective delivery to the skin compared to conventional ingredients.