Overview
Thymosin Beta 4 (TB4) is a functional peptide involved in cell migration and tissue regeneration, found in diverse tissue types. It interacts with actin to regulate cell migration and structural remodeling, and influences cell proliferation and differentiation processes. It is particularly known to play an important role in angiogenesis and wound healing processes. This recombinant TB4 is produced through an E. coli expression system, offering high purity and stable activity for application in a wide range of research and formulation contexts.
Applications
- Cell migration and motility studies
- Actin dynamics and cytoskeleton research
- Tissue regeneration and wound healing research
- Angiogenesis-related studies
- Skin regeneration and repair formulations
- Wound recovery and skin improvement products
- Hair growth and scalp care formulations
- Skin elasticity and structural improvement products
Properties
| Item | Description |
|---|---|
| Product name | TB4 (Thymosin beta 4, human) |
| Manufacturing Source | Recombinant, E. coli |
| Purity | ≥ 98 %, as determined by Coomassie stained SDS-PAGE. |
| Endotoxin | ≤ 0.4 EU/μg of protein |
| Protein Content | Quantified using validated methods |
| Biological activity | ED50 ≤ 1 μg/mL (HUVEC cell proliferation assay) |
| Predicted N terminal | Met1 |
| Molecular Weight | 5052.6 Da (44 amino acids). |
| Formulation | Sterile filtered through a 0.2 micron filtered 1X DPBS, pH 7.4. |
| Storage and Stability | Store at 2–8 °C for short-term use (1–2 weeks) and at -20 °C or below for long-term storage (> 2 weeks). Avoid repeated freeze–thaw cycles. |