Overview
Insulin-like Growth Factor 1 (IGF1) is a representative growth factor that mediates growth hormone action, regulating cell proliferation and differentiation. It acts across diverse tissue types and is involved in cell growth, migration, and regeneration processes. It also possesses physiological functions related to energy metabolism and tissue homeostasis maintenance. This recombinant IGF1 is produced through an E. coli expression system, offering high purity and stable activity for application in a wide range of research and formulation contexts.
Applications
- Cell proliferation assay (FDC-P1, etc.)
- Cell growth and differentiation studies
- Metabolism and signal transduction research
- Tissue regeneration and muscle/skeletal studies
- Skin regeneration and repair formulations
- Elasticity improvement and anti-aging products
- Damaged skin improvement and nourishing formulations
Properties
| Item | Description |
|---|---|
| Product name | IGF1 (Insulin-like growth factor 1, human) |
| Manufacturing Source | Recombinant, E. coli |
| Purity | ≥ 98 %, as determined by Coomassie stained SDS-PAGE |
| Endotoxin | < 0.4 EU/μg of protein |
| Protein Content | Quantified using validated methods |
| Biological activity | ED50 ≤ 50 ng/mL (FDC-P1 cell proliferation assay) |
| Predicted N terminal | Met1 |
| Molecular Weight | 7,785.9 Da (71 amino acids). |
| Formulation | Sterile filtered through a 0.2 micron filtered 1X DPBS, pH 7.4. |
| Storage and Stability | Store at 4 °C short term (1–2 weeks). Upon delivery aliquot. Store at -20 °C. Avoid freeze / thaw cycle. |