Product Overview

Overview

Noggin is a regulatory protein involved in cell differentiation and tissue formation, functioning as an inhibitor of the BMP signaling pathway. It plays an important role in neural tissue formation and various developmental processes, and is associated with cell differentiation and tissue regeneration. This recombinant Noggin is produced through an E. coli expression system, offering high purity and stable activity for application in a wide range of research and formulation contexts.

Application Area

Applications

Research Applications
  • BMP signaling inhibition research
  • Cell differentiation and neural induction studies
  • Stem cell and tissue formation research
  • Signal transduction and developmental biology studies
Cosmetic Applications
  • Skin cell differentiation regulation formulations
  • Skin regeneration and structural improvement products
  • Hair growth induction (anagen induction, follicle activation)
  • Hair follicle stem cell activation formulations
Properties

Properties

ItemDescription
Product nameNoggin (Noggin, human)
Manufacturing SourceRecombinant, E. coli
Purity≥ 98 %, as determined by Coomassie stained SDS-PAGE
Endotoxin< 0.4 EU/μg of protein
Protein ContentQuantified using validated methods
Biological activityED50 ≤ 100 ng/mL (C2C12 alkaline phosphatase inhibition assay)
Predicted N terminalMet1
Molecular Weight23178.7 Da (206 amino acids).
FormulationSterile filtered through a 0.2 micron filtered 50 mM sodium acetate, pH 5.0.
Storage and StabilityStore at 2–8 °C for short-term use (1–2 weeks) and at -20 °C or below for long-term storage (> 2 weeks). Avoid repeated freeze–thaw cycles.
Noggin Activity Data