Product Overview

Overview

Stem Cell Factor (SCF) is a cytokine-family protein that binds to the c-KIT receptor to regulate cell survival and proliferation. It plays an important role in hematopoiesis and promotes cell proliferation in combination with various growth factors. It also possesses physiological functions related to melanocyte and germ cell development. This recombinant SCF is produced through an E. coli expression system, offering high purity and stable activity for application in a wide range of research and formulation contexts.

Application Area

Applications

Research Applications
  • Hematopoiesis and stem cell research
  • c-KIT signaling pathway studies
  • Cell proliferation and survival research
  • Mast cell function and immune-related studies
Cosmetic Applications
  • Skin cell activation and regeneration formulations
  • Pigmentation-related cell regulation (melanocyte)
  • Scalp and hair-related functional formulations
Properties

Properties

ItemDescription
Product nameSCF (Stem cell factor, human)
Manufacturing SourceRecombinant, E. coli
Purity≥ 98 %, as determined by Coomassie stained SDS-PAGE.
Endotoxin≤ 0.4 EU/μg of protein
Protein ContentQuantified using validated methods
Biological activityED50 ≤ 100 ng/mL (TF-1 cell proliferation assay)
Predicted N terminalMet1
Molecular Weight18,589.4 Da (165 amino acids).
FormulationSterile filtered through a 0.2 micron filtered 20 mM sodium phosphate, 0.5% sucrose, pH 7.0.
Storage and StabilityStore at 2–8 °C for short-term use (1–2 weeks) and at -20 °C or below for long-term storage (> 2 weeks). Avoid repeated freeze–thaw cycles.
SCF Activity Data