Overview
Transforming Growth Factor Beta 2 (TGF-β2) is a multifunctional cytokine that regulates cell proliferation, differentiation, and migration, acting as a signaling protein across diverse cell types. It is involved in extracellular matrix production and tissue structure maintenance, and plays an important role in immune regulation and cell function control. This recombinant TGF-β2 is produced through an E. coli expression system, offering high purity and stable activity for application in a wide range of research and formulation contexts.
Applications
- TGF-β signaling pathway studies
- Cell differentiation and proliferation research
- Immune cell function and cytokine studies
- Extracellular matrix and fibrosis research
- Skin regeneration and structural improvement formulations
- Collagen synthesis and ECM regulation products
- Skin elasticity and anti-aging products
- Skin recovery and repair formulations
Properties
| Item | Description |
|---|---|
| Product name | TGF-β2 (Transforming growth factor beta 2, human) |
| Manufacturing Source | Recombinant, E. coli |
| Purity | ≥ 98 %, as determined by Coomassie stained SDS-PAGE. |
| Endotoxin | ≤ 0.4 EU/μg of protein |
| Protein Content | Quantified using validated methods |
| Biological activity | ED50 ≤ 0.05 ng/mL (HT-2 mouse T cell proliferation inhibition assay) |
| Predicted N terminal | Met1 |
| Molecular Weight | 12850.8 Da (113 amino acids). |
| Formulation | Sterile filtered through a 0.2 micron filtered 1 mM citrate, pH 3.5. |
| Storage and Stability | Store at 2–8 °C for short-term use (1–2 weeks) and at -20 °C or below for long-term storage (> 2 weeks). Avoid repeated freeze–thaw cycles. |