Overview
Fibroblast Growth Factor 1 (FGF1) is a growth factor that regulates cell survival and proliferation, with broad activity across diverse cell types. It is involved in cell differentiation, migration, and tissue regeneration processes, and has been associated with epithelial recovery and skin regeneration. This recombinant FGF1 is produced through an E. coli expression system, offering high purity and stable activity for application in a wide range of research and formulation contexts.
Applications
- Cell proliferation assay (HDFa, etc.)
- FGFR-based signal transduction research
- Cell migration and wound healing assay
- Angiogenesis and tissue regeneration studies
- Skin regeneration and repair formulations
- Elasticity improvement and anti-aging products
- Damaged skin recovery products
Properties
| Item | Description |
|---|---|
| Product name | FGF1 (Fibroblast growth factor 1, human) |
| Manufacturing Source | Recombinant, E. coli |
| Purity | ≥ 98 %, as determined by Coomassie stained SDS-PAGE |
| Endotoxin | < 0.4 EU/μg of protein |
| Protein Content | Quantified using validated methods |
| Biological activity | ED50 ≤ 20 ng/mL (HDFa cell proliferation assay) |
| Predicted N terminal | Met1 |
| Molecular Weight | 17460.0 Da (155 amino acids). |
| Formulation | Sterile filtered through a 0.2 micron filtered 10 mM sodium phosphate, 0.3 M Arg, pH 7.0 |
| Storage and Stability | Store at 2–8 °C for short-term use (1–2 weeks) and at -20 °C or below for long-term storage (> 2 weeks). Avoid repeated freeze–thaw cycles. |