Overview
Fibroblast Growth Factor 7 (FGF7), also known as Keratinocyte Growth Factor (KGF), is a protein that promotes the growth and proliferation of epithelial cells. It acts specifically on keratinocytes and is involved in the recovery and regeneration of skin and epithelial tissues. This recombinant FGF7 is produced through an E. coli expression system, offering stable activity and high purity for application in a wide range of research and formulation contexts.
Applications
- Cell proliferation assay (HaCaT and other keratinocytes)
- Epithelial cell growth and differentiation studies
- Wound healing and tissue regeneration research
- FGF receptor signal transduction studies
- Skin barrier strengthening and recovery formulations
- Skin regeneration and damage recovery products
- Sensitive skin improvement and protection formulations
Properties
| Item | Description |
|---|---|
| Product name | FGF7 (Fibroblast growth factor 7, human) |
| Manufacturing Source | Recombinant, E. coli |
| Purity | ≥ 98 %, as determined by Coomassie stained SDS-PAGE |
| Endotoxin | < 0.4 EU/μg of protein |
| Protein Content | Quantified using validated methods |
| Biological activity | ED50 ≤ 20 ng/mL (HaCaT cell proliferation assay) |
| Predicted N terminal | Met1 |
| Molecular Weight | 19014.9 Da (164 amino acids). |
| Formulation | Sterile filtered through a 0.2 micron filtered 1X DPBS, pH 7.4. |
| Storage and Stability | Store at 2–8 °C for short-term use (1–2 weeks) and at -20 °C or below for long-term storage (> 2 weeks). Avoid repeated freeze–thaw cycles. |