Product Overview

Overview

Insulin-like Growth Factor 2 (IGF2) is a growth factor that regulates cell proliferation and survival, acting across diverse tissue types. It plays an important role during development, and in adults is involved in energy metabolism and tissue maintenance. It regulates cell growth and signal transduction through interactions with IGF receptors and insulin receptors. This recombinant IGF2 is produced through an E. coli expression system, offering high purity and stable activity for application in a wide range of research and formulation contexts.

Application Area

Applications

Research Applications
  • Cell proliferation assay (MCF7, etc.)
  • Cell growth and apoptosis studies
  • Metabolism and signal transduction research
  • Development and tissue function studies
Cosmetic Applications
  • Skin regeneration and repair formulations
  • Elasticity improvement and anti-aging products
  • Damaged skin improvement and nourishing formulations
Properties

Properties

ItemDescription
Product nameIGF2 (Insulin-like growth factor 2, human)
Manufacturing SourceRecombinant, E. coli
Purity≥ 98 %, as determined by Coomassie stained SDS-PAGE
Endotoxin< 0.4 EU/μg of protein
Protein ContentQuantified using validated methods
Biological activityED50 ≤ 50 ng/mL (MCF7 cell proliferation assay)
Predicted N terminalMet1
Molecular Weight7,606 Da (68 amino acids).
FormulationSterile filtered through a 0.2 micron filtered 50 mM Tris-HCl, 100 mM NaCl, pH 9.0.
Storage and StabilityStore at 2–8 °C for short-term use (1–2 weeks) and at -20 °C or below for long-term storage (> 2 weeks). Avoid repeated freeze–thaw cycles.
IGF2 Activity Data