MITT Technology Platform · Since 2012
Skin-Penetrating
Functional Ingredients Solutions

Advanced Solutions for Skin and Hair Applications

PII-SKIN™

Next-generation functional ingredients
peptides, proteins, transomes
and high-purity recombinant proteins
designed with MITT technology.

84×
Skin Permeation
Enhancement
6 Countries
Patents
Registered
SCI
International
Publications
Stratum Corneum Epidermis Dermis ✦ Collagen Synthesis ✦ Wrinkle Reduction ✦ Brightening ✦ Skin Regeneration Subcutaneous tissue MITT-linked Growth Factor ↓

Application Area

Application Area

ProCell Therapeutics' delivery platform broadens the skin application of diverse functional ingredients, enabling use across hair loss treatment, wrinkle reduction, brightening, skin regeneration, anti-inflammation, and barrier strengthening.

Hair follicle stimulation
· Scalp activation
Hair Loss
Optimizes hair growth cycle via follicle stimulation and scalp conditioning
Collagen synthesis · Wrinkle reduction · Skin elasticity
Anti-Wrinkle
Promotes collagen synthesis and enhances skin elasticity
Melanin control
· Skin tone improvement
Brightening
Even skin tone through melanin control
Cell proliferation
· Tissue repair · Recovery
Skin Regeneration
Damaged skin recovery via cell proliferation and tissue repair
Oxidative stress control
· Anti-inflammation
Anti-Inflammation
Oxidative stress control and anti-inflammatory environment
Skin barrier recovery · Hydration · Protection
Barrier Strengthening
Restores barrier function and enhances moisture retention

Platform Technology

Core Technology

ProCell Therapeutics' MITT (Macromolecule Intracellular Transduction Technology)-based delivery system is the core platform enabling intracellular delivery of macromolecules and bioactive substances.

ProCell Therapeutics aims to be a world-class biopharmaceutical company, powered by its innovative core technology — MITT (Macromolecule Intracellular Transduction Technology).

Delivery Technology

Delivery Technology

The MTD-based delivery mechanism effectively transports diverse cargoes into cells, maximizing the biological activity of functional ingredients across broad applications.

What is MTD?

MTD (Macromolecule Transduction Domain)Macromolecule Cell-Penetrating Domain
Hydrophobic cell-penetrating peptide structure
8–15 amino acids · partially charged amino acids
Alpha-helix structure
Direct membrane penetration
ATP-independent delivery (no energy required)
Cargo — Deliverable Substances
Antibody · Peptide · Protein Chemical · Small Molecule siRNA iPSC Transcription Factor
Plasma Membrane Cytosol Nucleus Cell to Cell → Cargo MTD MTD-Cargo ✦ Successful intracellular delivery ATP-independent delivery

Key Delivery Features

ATP-Independent Direct Penetration
Direct membrane crossing with no energy consumption
🎯
Intracellular Precision Targeting
Precise delivery to nucleus and organelles
🔗
Cell-to-Cell Delivery
Continuous transfer to adjacent cells
📦
Universal Cargo Compatibility
Broad application — proteins, nucleic acids, nanoparticles and more
Therapeutic Drugs
Proteins / Peptides
Nucleic Acids
Nano Particles
Imaging Agents

Cellular and Tissue Penetration Technology

Cellular and Tissue Penetration

PII-SKIN™ transdermal delivery technology provides superior transdermal efficiency over conventional drug carriers, enabling optimal efficacy of bioactive substances according to time and concentration gradients.

MTD 투과능

Patent and Papers

Patents and Publications

Our proprietary MITT technology has been patented in 9 major countries and scientifically validated through multiple SCI-indexed international journals.

01
28 patents across 6 projects (9 major countries)
02
8 SCI · 1 KCI Journal Publications
03
Trademarks/Service Marks 23 registered, 1 pending
View All Patents and Papers →
특허 및 논문

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Samples are available upon inquiry.